Applications

• Safe biopharmaceutical production processes do not end with the purified product: Pathogenic and genetically modified organisms must be decontaminated according to their safety level.
• The decontamination must be carried out in accordance with local regulations. Most regulatory systems stipulate heat inactivation.
• Bioengineering has developed different concepts for customized kill tanks, which do not delay the production process.
• Conforming with local laws and customer requirements, these decontamination systems can be manually operated or automated in batch or continuous mode. Fully documentation available.

Killtank Strategies

Select the regulation-conform decontamination system for your process and plant/system:

Batchwise decontamination: Contaminated wastewater from the fermentor and/or downstream equipment is discharged into a collection tank. Once this tank is full, the wastewater is transferred into the kill tank, heat-sterilized with steam by means of an injector, cooled off again, and finally discharged into the sewer system. This process can be manually controlled or automated and documented.

Continuous decontamination: When a certain level is reached in the collection tank, the contaminated wastewater is circulated through the sterilization system. Here, it is pre-heated to 100° C and then pumped into the second heat exchanger, where it is heated to 140° C for 30 seconds. The inactivated wastewater is then cooled off in the third heat exchanger. Afterwards, it is discharged into the sewer system. A heat-recovery system is also integrated in the continuous decontamination. The complete process can be automated and documented.